I have tried several professional backpacks both for bicycling and running to work. I frequently have to carry my laptop back and forth and always a change of clothes, and a 10 k run with a backpack that is moving around a lot is simply too uncomfortable. Having just received my new Backpack Pro 2.0 I have run 40 k in 7 days, first with just a simple change of clothes but the last runs with a laptop as well. Works beautifully and so much more "stuck" to my back. Can't say anything about longevity yet of course, but if it holds up it is definitely a winner and good running companion.